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Daniel Ambruso, MD

Professor, Pediatrics-Hematology / Oncology
Ambruso
Clinic Phone: 720-777-6511

Specialties: Pediatrics, Pediatric Hematology / Oncology

Locations: Aurora - University of Colorado Hospital (UCH), Aurora - Children's Hospital Colorado

Clinical Interest for Patients: I am interested in Qualitative and Quantitative Disorders of Neutrophils, Allo and Autoimmune Disorders of Red Cells and Platelets, General Hematology and Transfusion Medicine. Additionally, I have focused on the establishment of a Cord Blood Bank and the Bonfils Cord Blood Services at Bonfils Blood Center, which provides Stem Cells for Hematopoietic Stem Cell Transplantation.
Conditions & Treatments:
  • Blood / Lymphatic System - Bleeding Disorders
  • Blood / Lymphatic System - Blood Disorders
  • Cancers
General Information
Gender: Male
Language: English
Education and Training
Medical Schools
MD, University of Rochester School of Medicine and Dentistry (1973)

Undergraduate Schools
BS, Georgetown University (DC) (1969)

Residency Program
Case Western Reserve University (MetroHealth) Program, Pediatrics (1976)

Fellowships
University of Colorado, Pediatrics - Pediatric Hematology / Oncology (1978)
National Jewish Medical and Research Center, Allergy and Immunology (1979)

Specialty Information
Specialties
Pediatrics, Board Certification (1978)
Pediatrics - Pediatric Hematology / Oncology, Board Certification (1978) Recertification (2010)

Conditions & Treatments:
  • Blood / Lymphatic System - Bleeding Disorders
  • Blood / Lymphatic System - Blood Disorders
  • Cancers

Practice Locations
Hospital Affiliation
Children's Hospital Colorado
University of Colorado Hospital

Clinical Locations
University of Colorado Hospital (UCH)
12605 E. 16th Ave.
Aurora, CO 80045
(720) 848-0000 
Website

Children's Hospital Colorado
13123 East 16th Avenue
Aurora, CO 80045
720-777-1234
800-624-6553
Appointments: 720-777-1234
Website

Job Titles
Academic - Professor
Other - Director, Research Belle Bonfils Memorial Blood Center
Other - Associate Medical Director, Belle Bonfils Memorial Blood Center

Department, Section / Division
Pediatrics, Pediatrics-Hematology / Oncology

Center Affiliations
Bonfils Blood Center

Professional Memberships
American Pediatric Society - Member
Denver and Colorado Medical Societies - Member
American Society of Hematology - Member
AABB, formerly American Association of Blood Banks - Member
Society for Pediatric Research - Member
Western Society for Pediatric Research - Member
Research & Grants
Website
http://www.ncbi.nlm.nih.gov/pubmed?term="Ambruso DR"[Author]

Research Interests
I am interested in Neutrophil Function in the Following Clinical Groups: Thermal Injury and Trauma Patients; Newborn Patients; Patients with Absence of Specific Granules; Patients with Glycogenosis lb; and Patients with Chronic Granulomatous Disease. I, also, focus on Chronic Transfusion Therapy and Iron Overload in Patients with Chronic Anemia. Additionally, I am interested in Antibody-Mediated Disorders of Platelets and Neutrophils, as well as the Generation of Lysophosphatidylcholines in Stored Blood Components and their relationship to the Pathophysiology of Transfusion Related Acute Lung Injury (TRALI).
Teaching
Professor (1993)
School of Medicine
Pediatrics

Information for Referring Providers
Clinical Interests for Referring Providers: I am interested in Qualitative and Quantitative Disorders of Neutrophils, Alloimmune and Autoimmune Disorders of Red Cells and Platelets, General Hematology and Transfusion Medicine. Additionally, I have focused on the establishment of a Cord Blood Bank and the Bonfils Cord Blood Services at Bonfils Blood Center, which provides Stem Cells for Hematopoietic Stem Cell Transplantation.

Research Interest for Referring Providers: I am interested in the Respiratory Burst Activity and Bactericidal Activity of Neutrophils and Monocytes. Additionally, I focus on the Priming Mechanisms of Neutrophil Oxidase and the Development of Clinical Models of Excess Inflammation. I, also, concentrate on Blood Component Storage and Pathogen Reduction, as well as the Counting of Residual Leukocytes in Leukoreduced Blood Components. I collaborate with COBE BCT to develop new equipment and systems to separate platelets from whole blood. Additionally, I am interested in Alloimmunization in Response to Red Cell and Platelet Transfusions.

Hospital Affiliation
Children's Hospital Colorado
University of Colorado Hospital

Clinical Locations: Aurora - University of Colorado Hospital (UCH), Aurora - Children's Hospital Colorado

Clinic Phone: 720-777-6511

Fax Phone: 720-777-7279
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