University of Colorado Seal
Join our community:TwitterFacebook

Yogendra Raol, MD, MSc, PhD

Assistant Professor, Pediatrics-Neurology
 
Clinic Phone: 720-777-6895

Specialty: Neurology

Location: Aurora - Children's Hospital Colorado

General Information
Gender: Male
Language: English
Education and Training
Medical Schools
MD, University of Melbourne (2002)

Graduate Schools
MSc, University of Baroda, Baroda, India (1995)
PhD, National Institute of Mental Health and Neurosciences, Bangalore, India (2000)

Undergraduate Schools
BSc, Gujarat University (Ahmedabad, India) (1993)

Fellowships
Children's Hospital of Philadelphia Program, Psychiatry and Neurology - Neurology (2005)

Specialty Information
Specialty
Psychiatry and Neurology - Neurology

Practice Locations
Hospital Affiliation
Children's Hospital Colorado

Clinical Location
Children's Hospital Colorado
13123 East 16th Avenue
Aurora, CO 80045
720-777-1234
800-624-6553
Appointments: 720-777-1234
Website

Job Titles
Academic - Assistant Professor

Department, Section / Division
Pediatrics, Pediatrics-Neurology

Professional Memberships
Association of Physiologist and Pharmacologist of India - Member
American Epilepsy Society - Member
Indian Epilepsy Society - Member
Society for Neuroscience - Member
Research & Grants
Research Interests
My research involves studying the changes that occur following an insult or an injury and finding a treatment that can prevent or reverse these changes and alleviate injury-induced long-term neurologic disability.
Information for Referring Providers
Research Interest for Referring Providers: My research involves studying the changes that occur following an insult or an injury and finding a treatment that can prevent or reverse these changes and alleviate injury-induced long-term neurologic disability. The risk of seizures is greatest in the neonatal period. Therefore, my current research studies focus on finding a treatment that can effectively treat neonatal seizures without affecting the normal development. More than 76% of doctors worldwide use phenobarbital as the first treatment option to stop neonatal seizures. However, phenobarbital, which effectively treats seizures in adult patients, is ineffective in treating seizures in more than 50% of neonatal patients. Moreover, early life treatment with phenobarbital has been associated with several detrimental effects including reduced cognitive performance. All available antiepileptic drugs have been developed using adult animal models and tested clinically in adult patients. However, significant differences exist between the developing and mature brain in terms of its anatomy, neurochemistry and electrophysiology. Due to these developmental differences, the immature brain responds differently to insult and treatment than the mature brain. Therefore, to find the most efficacious treatment for early childhood diseases, it is imperative to target age-specific mechanisms and test new therapies in neonatal disease models. In the lab, we are currently testing efficacy of a potassium channel opener to treat neonatal seizures in an animal model. We chose to target potassium channels to treat neonatal seizures because in early-life due to underdeveloped GABA mediated inhibition (phenobarbital mediates its anti-seizure activity by increasing GABA mediated inhibition), potassium channels play an important role in controlling excitation.

Hospital Affiliation
Children's Hospital Colorado

Clinical Location: Aurora - Children's Hospital Colorado

Clinic Phone: 720-777-6895
Filter Results
Keyword

Name

Specialties

Hospitals

Conditions Treated
Gender
Male
Female
Departments

Centers & Institutes

Clinical Locations

Languages