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Doctor Holly Wyatt, Associate Professor of Endocrinology, Metabolism & Diabetes, is the medical director at the Anschutz Health and Wellness Center. She is also a lead researcher in the ENDO trial, which could lead to a safe and affordable alternative to gastric bypass surgery.
The ENDO trial will test alternative approaches to treating type 2 diabetes, focusing on the EndoBarrier.

“The EndoBarrier is a tube-shaped liner that forms that physical barrier between the food that you’re eating and the initial part of your intestine,” Dr. Wyatt said. “There seems to be some part of bypassing that part of the gut, at least in the surgical models, that seems to be really good in controlling diabetes.”

Depending on the results of the research, the EndoBarrier could become an alternative to bariatric surgery. This would especially help patients with diabetes or obesity who aren’t good candidates for surgery. The U.S. National Institutes of Health currently recommends gastric bypass surgery for people with diabetes and a Body Mass Index of at least 40.

This cutting edge technology is the latest of several high-profile research projects to come out of the CU Anschutz Health and Wellness Center, which opened only last year, earning the center’s team of dieticians, physicians and wellness experts a place in the national spotlight.

Dr. Wyatt and her team of Health and Wellness Center researchers are looking for 20 adults between the ages of 21 and 65 to take part in the ENDO trial. Test subjects must have type 2 diabetes and must have a body mass index between 30 and 50 and a hemoglobin A1C count between 8 and 10. For more information, call 1-888-978-8399.

Read the full article from the Aurora Sentinel on the ENDO trial here.

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