Melanie Cree, MD, PhD
Associate Professor, Pediatrics-Endocrinology

Director, Multi-Disciplinary PCOS clinic
Clinic 720-777-1234
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Gender: Female
Languages: English
Department, Section/Division: Pediatrics-Endocrinology
Medicine-Endocrinology/Metabolism/Diabetes

Practice Locations

Children's Hospital Colorado Anschutz Medical Campus
13123 East 16th Ave
Aurora, CO 80045
720-777-1234
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Hospital Affiliation
  • Children's Hospital Colorado
Center Affiliations

Specialty Information

Specialties
  • Pediatrics - Pediatric Endocrinology, Board Certification (2015)
  • Pediatrics, Board Certification (2012)
Conditions & Treatments
  • Child and Teen Health
  • Pediatric Diseases and Conditions
  • Endocrine System (Hormones)
Clinical Interest for Patients
I see most pediatric endocrine conditions. I have a special interest in polycystic ovarian syndrome and oversee a special clinic for girls with this condition who are also overweight, to try to offer a complete treatment plan in 1-2 visits.

Care Philosophy
My overall philosophy is try to practice personalized medicine as much as possible, and make sure my recommended therapies are right for the medical condition, the patient and the family.

Personal Interests
In my spare time, I enjoy spending time with my family, running, snowboarding, gardening and photography.

Volunteer Activities
I spend time supporting activities in the schools and for children's health.

Education & Training

Medical Schools:
  • MD, University of Texas Medical Branch School of Medicine (2007)

Graduate Schools:
  • PhD, University of Texas Medical Branch (2007)

Undergraduate Schools:
  • AB, Bryn Mawr College (PA) (1999)

Internships:
  • University of Colorado (Children's Hospital Colorado) Program (2009)

Residency Program:
  • University of Colorado (Children's Hospital Colorado) Program, Pediatrics (2011)

Fellowships:
  • University of Colorado (Children's Hospital Colorado) Program, Pediatric Endocrinology (2014)

Recognition & Awards

  • Highest Patient Satisfaction Award, Children's Hospital Colorado (2017)
  • “Best of 2017” article selection, Endocrine Society (2017)
  • 1st annual Carmel Prize for Academic Excellence, Western Society for Pediatric Medicine (2016)
  • Early Investigator Award, Endocrine Society (2016)
  • Junior Faculty Outstanding Abstract Award, Endocrine Society (2015)
  • Fellow's Clinical Research Award, Society for Pediatric Research (2014)
  • Fellows Travel Award, Pediatric Endocrine Society (2014)
  • Scholar, Western Region of the American Federation for Medical Research (2013)
  • Women's Health Fellowship, Endocrine Society (2013)
  • Research Fellowship, Pediatric Endocrine Society (2013)

Professional Memberships

  • AE-PCOS Society, Member
  • American Diabetes Association (ADA), Member
  • American Heart Association (AHA), Member
  • American Physiological Society (APS), Member
  • Endocrine Society, Member
  • Obesity Society, Member
  • Pediatric Endocrine Society (PES), Member

Research & Grants

https://profiles.ucdenver.edu/display/7031580
Grants
  • Role of semaglutide in restoring ovulation in youth and adults with polycystic ovary syndrome (2023)
    NIH - NICHD, $2100000
  • The presentation and medical course of PCOS in adolescents across the United States (2023)
    NIH NICHD, $580000
  • Amino Acids and Pediatric Hepatic Steatosis (2023)
    NIH NIDDK, $1200000
  • “Innovating Methods for AssessinG INsulin Action in Type ONe diabetes (IMAGINation) (2021)
    Juvenile Diabetes Research Foundation, $400000
  • Impact of GLP-1 on hepatic fat and energy utilization in obese girls with polycystic ovarian syndrome (2019)
    NIH - NIDDK, $2500000
  • Use of essential amino acid supplementation to decrease metabolic disease in high risk obese girls with PCOS (2018)
    Doris Duke Charitable Foundation, $495000
  • Do alterations in serum testosterone mediate systemic insulin sensitivity and hepatic health via the gut microbiota? (2018)
    Colorado CTSI, $30000
  • Non-invasive assessment of liver glucose metabolism in obese girls (2015)
    Boettcher Webb-Waring, $225000
  • Influence of peripheral insulin resistance and hepatic lipogenesis on liver fat in obese PCOS girls (2015)
    NIDDK K23, $700000
  • Modeling Hepatic and Adipose IR with stable isotopes during an oral glucose tolerance test (2014)
    Childrens Hospital Colorado, $20000
  • The role of hepatic lipogenesis in hepatic insulin resistance in obese girls with hyperandrogenism (2014)
    BIRCWH/NIH, $200000
  • Impact of obesity and androgens on CV function and organ specific IR in youth with PCOS (2013)
    American Heart Association, $150000
Research interests for Patients:
My research interests are focused on how insulin works in youth with polycystic ovarian syndrome or diabetes. We are trying to better understand how high insulin levels cause disease, so that we can prevent related conditions such as fatty liver disease or heart disease and develop new therapies.

Information for Referring Providers

Clinical Interests for Referring Providers
In addition to general pediatric Endocrinology, I have a special interest in polycystic ovarian syndrome, and I oversee a multi-disciplinary clinic for girls with PCOS who also struggle with obesity. Providers in this clinic include Nutrition, psychology, pediatric Endocrinology, Gynecology, Dermatology, exercise physiology.

Research Interest for Referring Providers
I perform research in insulin resistance in girls with PCOS, youth with type 1 diabetes and type 2 diabetes. My interests are focused on the interaction between glucose and fat metabolism and how the interplay leads to insulin resistance, fatty liver disease and early cardiovascular disease.
Office Phone: (720) 777-6128

CV Cree.Melanie.CV.7.13.2024.docx